MOLECULAR SUBTYPES OF COLORECTAL CANCER IN PRE-CLINICAL MODELS SHOW DIFFERENTIAL RESPONSE TO TARGETED THERAPIES: TREATMENT IMPLICATIONS BEYOND KRAS MUTATIONS.

Molecular subtypes of colorectal tumors are associated with prognosis and prediction for treatment benefit from chemotherapy.The purpose of this study was two-fold: 1) to determine the association of colorectal (CRC) molecular subtypes with response to targeted therapies in pre-clinical models and 2) to identify treatments for CRC stem-like subtype

Background: Several studies investigated the mental health needs of hospital staff in Greece during the debt crisis era.Yet, no relevant data are available regarding the mental health of hospital staff after this period.The aims of this Places Art study are: 1) To investigate the prevalence of clinically significant depression and anxiety in health

The present work investigates the effect of precursor concentration (mc) on the structural, optical, morphological and electrical conductivity properties Bathroom Accessories of In2S3 thin films grown on amorphous glass substrates by nebulized spray pyrolysis (NSP) technique.The mixed phase of cubic and tetragonal structure of In2S3 thin films at h

Platycodon grandiflorus roots have been used as a foodstuff and traditional medicine for thousands of years in East Asia.In order to increase the root development of P.grandiflorus, cultivators removed the inflorescences, suggesting the possible negative effect of flowering on root development.This indicates that the genetic improvement of P.grandi

Stuffed Toy Xiufang Hong,1,2 Xujiao Chen,2 Jiaojiao Chu,2 Shanshan Shen,2 Qichen Chai,2 Gaobo Lou,2 Lingyan Chen2 1Zhejiang Chinese Medical University, 2Department of Geriatrics, Zhejiang Hospital, Hangzhou, Zhejiang, People’s Republic of China Objective: To investigate whether there is a difference in balance function between older persons w